Treatment

Creyos Cognitive Assessments for ADHD: What They Measure and Why It Matters

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Here's a problem I've seen play out hundreds of times in my clinical practice. A child gets an ADHD diagnosis. A treatment plan is built. The family tries it for six months. Some things seem better. Some things don't. And no one can quite say why — or measure what actually changed.

The missing piece, almost always, is objective data. Not parent ratings, not teacher checklists, not clinical impression — actual measurement of what the brain can and can't do, before treatment and after. Without that baseline, we're flying blind.

Creyos cognitive assessments are one of the best tools I know for establishing that baseline and tracking real change over time. Let me explain what they measure and why it matters.

What Is Creyos?

Creyos (formerly Cambridge Brain Sciences) is a computerized cognitive assessment platform developed by neuroscientists at the University of Cambridge. It measures 12 core cognitive domains through short, gamified tasks that can be completed in 20–30 minutes on any device. The tasks were designed to assess the same cognitive functions that decades of neuropsychological research have identified as central to how the brain thinks, remembers, plans, and focuses.

The domains Creyos measures include working memory, sustained attention, response inhibition, processing speed, reasoning, planning, and cognitive flexibility — a profile that maps almost exactly onto the cognitive functions most affected by ADHD. This isn't coincidence. These are the same functions that the prefrontal cortex manages, and the prefrontal cortex is the brain region most consistently underperforming in ADHD.

Creyos compares each person's scores to age-matched norms, generating percentile scores in each domain. That comparison is what makes it clinically useful: you can see not just whether working memory is below average, but how far below — and in which specific tasks the gap is largest.

Why the ADHD Brain Reveals Itself Under Pressure

ADHD doesn't always show up in casual conversation or even in a clinical interview. Many children with ADHD are charming, articulate, and apparently organized for the first ten minutes of any interaction. The deficit becomes visible under pressure — specifically, under the pressure of timed, demanding cognitive tasks that require sustained attention, accurate inhibition of impulsive responses, and real-time working memory management.

Creyos includes several timed tasks that expose exactly these vulnerabilities. The key ones for ADHD assessment:

The key pattern to look for: low scores on timed tasks with better (or normal) scores on untimed tasks. This gap — the ability to perform accurately when time doesn't matter, but not when it does — is one of the most reliable cognitive signatures of ADHD.

Different ADHD Subtypes, Different Cognitive Profiles

One of the most valuable things Creyos offers is the ability to distinguish between ADHD subtypes based on cognitive patterns, not just behavioral descriptions. This matters for treatment because a Pooh-type inattentive profile and a Tigger-type hyperactive profile have the same diagnosis but different cognitive vulnerabilities — and they respond to different interventions.

Creyos as a Treatment Tracking Tool

The diagnostic use of Creyos is valuable. The treatment-monitoring use may be even more valuable. When you establish a baseline before treatment begins and then reassess at 10-session intervals, you can see whether the intervention is actually changing the brain — not just whether the parent thinks the child is doing better.

Working memory scores going up after eight weeks of neurofeedback. Double Trouble scores improving after three months of CES and Dual-N-Back training. Processing speed normalizing after dietary changes and consistent sleep. These are measurable outcomes, not impressions. They allow you to make evidence-based decisions about whether to continue, modify, or redirect the treatment plan.

This is how treatment planning should work. Not "let's try this for a year and see how it goes" — but "here's where we are, here's what we're targeting, and here's how we'll know we're getting there."

Pairing Creyos with Self-Report Inventories

Creyos measures what the brain can do. Self-report inventories measure what the person experiences. Both are necessary — because ADHD affects subjective experience in ways that cognitive testing alone doesn't capture.

The most useful pairings:

What To Do Starting Today

Seeing What the Brain Is Actually Doing

ADHD has too long been treated on the basis of what people say — reports, ratings, impressions, observations. These are important. But they're not the same as measurement. A child who has "gotten better" at masking their struggles still has the same brain. A child whose scores on cognitive inhibition and sustained attention have moved from the 10th to the 40th percentile has a different brain than they had six months ago.

That's the difference between managing symptoms and actually changing the underlying condition. Creyos can show you which one you're doing. And that knowledge changes everything about what comes next.

References

  1. Hampshire, A., et al. (2012). Fractionating human intelligence. Neuron, 76(6), 1225–1237.
  2. Barkley, R.A. (2015). Attention-Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment (4th ed.). Guilford Press.
  3. Faraone, S.V., et al. (2021). The World Federation of ADHD International Consensus Statement. Neuroscience & Biobehavioral Reviews, 128, 789–818.
  4. Willcutt, E.G., et al. (2005). Validity of the executive function theory of ADHD. Biological Psychiatry, 57(11), 1336–1346.
  5. Spitzer, R.L., et al. (2006). A brief measure for assessing generalized anxiety disorder: The GAD-7. Archives of Internal Medicine, 166(10), 1092–1097.
About the author. Dr. Douglas Cowan, Psy.D., is a Licensed Marriage and Family Therapist with 40 years of clinical experience and over 35 years in neurofeedback, licensed and practicing since 1988. Read his full credentials →